Retinoic Acid Ester (5% Hydroxypinacolone Retinoate + 4-Butylresorcinol)

Best Way To Use

Slowly introduce into an evening routine, starting with application three times a week and gradually increase application frequency. Apply two to three drops in the evening to face, neck and décolletage. Do not use with other retinoid products.

Suitable Skin Types

• Combination
• Oily

Say Goodbye To

• Dullness / poor complexion
• Textural irregularities
• Uneven skin tone
• Fine lines and wrinkles

Contraindications

Alpha Hydroxy Acids, Beta Hydroxy Acids, Polyhydroxy Acids

• Avoid layering with direct acids to avoid over stimulation of the skin and impairing the barrier.

For Your Safety

• Patch test before use.
• Keep away from children.
• Store at room temperature.
• Do not use on broken skin.
• Use sunscreen every morning.
• If irritation occurs, stop use. If problem persists, see a doctor.
• Avoid contact with eyes.
• Not suitable for use if pregnant or breastfeeding.

References

1. L Kolbe  1 , T Mann, W Gerwat, J Batzer, S Ahlheit, C Scherner, H Wenck, F Stäb. 4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation. J Eur Acad Dermatol Venereol. 2013 Jan;27 Suppl 1:19-23.
2. Giornale Italiano di Dermatologia e Venereologia, 2016/03, Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.
3. Ruth, N., and T. Mammone. “1310 Anti-aging effects of retinoid hydroxypinacolone retinoate on skin models.” Journal of Investigative Dermatology 138.5 (2018): S223.